Dr. Darryl Nater - Skalierbare Elektrosynthese
- Dr. Darryl Frédéric Nater
- Gruppenleiter
- Skalierbare Elektrosynthese
- Elektrosynthese
- +49 (0)208 306 - 3155
- darryl.nater(at)cec.mpg.de
- Raum:
Vita
| B.Sc | ETH Zürich, Switzerland (2013-2016) |
| M.Sc | ETH Zürich, Switzerland (2016-2018) |
| Ph.D. | ETH Zürich, (Prof. Dr. Christophe Copéret, Switzerland (2018-2022) |
| Postdoc | University of Mainz and MPI CEC, Elektrosynthesis – Prof. Dr. Siegfried R. Waldvogel (SNSF postdoc.mobility fellowship), (2022-2025) |
| Group Leader | Scalable Electrosynthesis, MPI CEC (since 2025) |
Publikationen
(1) Feng, Z.; Nater, D.; Leautier, T.; Sintes, M.; Weyhermüller, T.; Waldvogel, S. R. Electrochemical Hofmann Rearrangement to Hydrazides. ChemElectroChem 2026, accepted.
(2) Frank, N.; Chaudhari, M. B.; Leutzsch, M.; Helmich-Paris, b.; Bruzzese, P. C.; Nater, D.; Nöthling, N.; Schnegg, A.; Waldvogel, S. R.; List, B. The photohydrolysis of furans. Science 2026, 391, 267-274. DOI: 10.1126/science.aec6532.
(3) Lohmann, A. H. J.; Kerackian, T.; Burger, A.; Pickenbrock, J.; Nater, D.; Leong, S. X.; Aspuru-Guzik, A.; Waldvogel, S. R. Bayesian Optimized Electrosynthesis of Azobenzenes in a Self- Optimizing Flow Set-up: from DoE-guidance to Gram-Scale Preparation. chemrxiv 2026. DOI: 10.26434/chemrxiv-2026-8rd5c.
(4) Nater, D. F.; Zhao, R.; Rocker, J.; Boche, C.; Yun, D.; Werner, B.; Löb, P.; Ziogas, A.; Waldvogel, S. R. Hectogram-Scale Synthesis of Carbamates Using Electrochemical Hofmann Rearrangement in Flow. Org. Process Res. Dev. 2025, 29, 2370-2377. DOI: 10.1021/acs.oprd.5c00234.
(5) Nater, D. F.; de Zwart, F. J.; Kaeffer, N.; Coperet, C. Initiating olefin metathesis: alkylidenes from molecular Mo(iv)-oxo species, olefins and base-promoted proton transfer. Chem Sci 2025, 16, 23351-23356. DOI: 10.1039/d5sc06662j.
(6) Nater, D. F.; Hendriks, P.; Waldvogel, S. R. Electrochemical Hofmann rearrangement at high current densities in a simple flow setup. Molecular Catalysis 2024, 554, 113823. DOI: 10.1016/j.mcat.2024.113823.
(7) Bieniek, J. C.; Nater, D. F.; Eberwein, S. L.; Schollmeyer, D.; Klein, M.; Waldvogel, S. R. Efficient and Sustainable Electrosynthesis of N-Sulfonyl Iminophosphoranes by the Dehydrogenative P–N Coupling Reaction. JACS Au 2024, 4 (6), 2188-2196. DOI: 10.1021/jacsau.4c00156.
(8) Zlatar, M.; Nater, D.; Escalera-López, D.; Joy, R. M.; Pobedinskas, P.; Haenen, K.; Copéret, C.; Cherevko, S. Evaluating the stability of Ir single atom and Ru atomic cluster oxygen evolution reaction electrocatalysts. Electrochimica Acta 2023, 444. DOI: 10.1016/j.electacta.2023.141982.
(9) Berkson, Z. J.; Zhu, R.; Ehinger, C.; Latsch, L.; Schmid, S. P.; Nater, D.; Pollitt, S.; Safonova, O. V.; Bjorgvinsdottir, S.; Barnes, A. B.; et al. Active Site Descriptors from (95)Mo NMR Signatures of Silica-Supported Mo-Based Olefin Metathesis Catalysts. J Am Chem Soc 2023, 145 (23), 12651-12662. DOI: 10.1021/jacs.3c02201.
(10) Nater, D. F.; Kaul, C. J.; Latsch, L.; Tsurugi, H.; Mashima, K.; Coperet, C. Olefin Metathesis Catalysts Generated In Situ from Molybdenum(VI)-Oxo Complexes by Tuning Pendant Ligands. Chemistry 2022, 28 (22), e202200559. DOI: 10.1002/chem.202200559.
(11) Nater, D. F.; Boudjelel, M.; Lätsch, L.; Schrock, R. R.; Copéret, C. W‐oxo Adamantylidenes: Stable Molecular Precursors for Efficient Silica‐Supported Metathesis Catalysts. Helvetica Chimica Acta 2022, 105 (4). DOI: 10.1002/hlca.202200013.
(12) De Jesus Silva, J.; Pucino, M.; Zhai, F.; Mance, D.; Berkson, Z. J.; Nater, D. F.; Hoveyda, A. H.; Coperet, C.; Schrock, R. R. Boosting the Metathesis Activity of Molybdenum Oxo Alkylidenes by Tuning the Anionic Ligand sigma Donation. Inorg Chem 2021, 60 (10), 6875-6880. DOI: 10.1021/acs.inorgchem.0c03173.
(13) Rochlitz, L.; Searles, K.; Nater, D. F.; Docherty, S. R.; Gioffrè, D.; Copéret, C. A Molecular Analogue of the C−H Activation Intermediate of the Silica‐Supported Ga(III) Single‐Site Propane Dehydrogenation Catalyst: Structure and XANES Signature. Helvetica Chimica Acta 2021, 104 (7). DOI: 10.1002/hlca.202100078.
(14) Nater, D. F.; Paul, B.; Lätsch, L.; Schrock, R. R.; Copéret, C. Increasing Olefin Metathesis Activity of Silica‐Supported Molybdenum Imido Adamantylidene Complexes through E Ligand σ‐Donation. Helvetica Chimica Acta 2021, 104 (11). DOI: 10.1002/hlca.202100151.
(15) Calvo, R.; Le Tellier, A.; Nauser, T.; Rombach, D.; Nater, D.; Katayev, D. Synthesis, Characterization, and Reactivity of a Hypervalent-Iodine-Based Nitrooxylating Reagent. Angew Chem Int Ed Engl 2020, 59 (39), 17162-17168. DOI: 10.1002/anie.202005720.
Gruppenmitglieder
Forschung im Team "Skalierbare Elektrosynthese"
In the “Scalable Electrosynthesis” team, we work on the development of electro-organic processes and reactors, thus providing fundamental understanding on the influences of reactors on electrosynthetic reactions, while also providing a basis for broader application of electrosynthesis.
Development and Scaling of Electrosynthetic Processes
One of our research lines is the identification and exploration of novel electrochemical transformations. We are particularly interested in scaling those reactions after their initial development, thus providing tools for general synthetic chemists to use electrosynthesis themselves.
See:
- JACS Au 2024, 4 (6), 2188-2196. DOI: 10.1021/jacsau.4c00156.
- Mol. Catal. 2024, 554, 113823. DOI: 10.1016/j.mcat.2024.113823.
- Org. Process Res. Dev. 2025, DOI: 10.1021/acs.oprd.5c00234
New Screening and Optimization Protocols for Electrosynthesis
When optimizing electrochemical reactions, both traditional chemical parameters (such as temperature and concentration) and electrochemical parameters (such as current density and charge) need to be investigated. This results in a parameter space that is both large and complex. In order to efficiently navigate this space, we are harnessing AI-based tools and advanced optimization algorithms to find the shortest path from an initial hit on a new electrosynthetic process to an optimized reaction.
See:
- ChemElectroChem 2024, 11 (18), e202400360. DOI: 10.1002/celc.202400360.
- ChemElectroChem 2021, 8 (14), 2621-2629. DOI: 10.1002/celc.202100318.
Design of Novel Reactors for Electro-Organic Reactions
Electro-organic reactions involve working with two spatially separated areas (the cathode and anode) where highly reactive species are generated. How these two areas interact is largely determined by the employed reactor geometry. As part of our efforts to understand the interaction of reactivity and reactor geometry, we are designing and testing novel reactors for electro-organic transformations.